Analysis of Interleukin-17, Interleukin-23, neopterin and Nesfatin-1 levels in the sera of Hashimoto patients

Background: Hashimoto's thyroiditis (HT) is an autoimmune disorder affecting the thyroid gland and may present as goiter or atrophic that result in various metabolic inflammatory disorders. The aim of this study to determine changes serum levels interleukin-17 (IL-17), IL-23, neopterin, nesfatin-1 parameters HT patients evaluate possible relationship among these parameters. Methods: 90 30 healthy individuals were included study. Demographic data recorded detailed physical examinations performed. IL-17, measured samples participants by ELISA method. Results: Serum significantly higher lower group compared control group. Statistically significant differences observed between all groups except euthyroid versus treated with levothyroxine for at 0.05 level. Conclusion: neopterin involved etiopathogenesis HT. Weight gain due low level rather than throid hormone deficiency. These variables could be used potential biomarkers diagnosis, prognosis fellow up disease.